The Guardian reports on a new study that shows glyphosate can have disrupting effects on sexual development, genes and beneficial gut bacteria at doses considered safe. Glyphosate is the core ingredient in Monsanto’s Roundup herbicide and levels found in the human bloodstream have spiked by more than a 1,000% in the last two decades.
The substance was recently relicensed for a shortened five-year lease by the EU. But scientists involved in the new glyphosate study say their results show that it poses “a significant public health concern”.
One of the report’s authors, Daniele Mandrioli, at the Ramazzini Institute in Bologna, Italy, said significant and potentially detrimental effects from glyphosate had been detected in the gut bacteria of rat pups born to mothers, who appeared to have been unaffected themselves.
“It shouldn’t be happening and it is quite remarkable that it is,” Mandrioli said. “Disruption of the microbiome has been associated with a number of negative health outcomes, such as obsesity, diabetes and immunological problems.”
Prof Philip J Landrigan, of New York’s Icahn School of Medicine, and also one of the research team, said: “These early warnings must be further investigated in a comprehensive long-term study.” He added that serious health effects from the chemical might manifest as long-term cancer risk: “That might affect a huge number of people, given the planet-wide use of the glyphosate-based herbicides.”
In attempts to dismiss the study’s findings a Monsanto spokesman said “The Ramazzini Institute is an activist organisation with an agenda that they have not disclosed as part of their crowdfunding efforts. They wish to support a ban on glyphosate and they have a long history of rendering opinions not supported by regulatory testing agencies.”
The new crowdfunded pilot study which the Ramazzini Institute compiled with Bologna University and the Italian National Health Institute observed the health effects of glyphosate on Sprague Dawley rats, which had been dosed with the US EPA-determined safe limit of 1.75 micrograms per kilo of body weight.
The study’s three peer-reviewed papers will be published in Environmental Health later in May, ahead of a €5m follow-up study that will compare the safe level against multiple other doses.